Rhabdomyosarcoma Cells Produce Their Own Extracellular Matrix With Minimal Involvement of Cancer-Associated Fibroblasts: A Preliminary Study
BackgroundThe interplay between neoplastic cells and surrounding extracellular matrix (ECM) is one of the determinant elements for cancer Disinfectants growth.The remodeling of the ECM by cancer-associated fibroblasts (CAFs) shapes tumor microenvironment by depositing and digesting ECM proteins, hence promoting tumor growth and invasion.While for e